I don't know what the travel time is to Colombia or Puerto Rico (although I imagine at least the latter is less), but the cost per day and travel time of going to Spain for just a week would take it off of the list if it were me. I think you should hold off on that trip until you have more time. That said, I'd love to go to Valencia.
I've never been to South or Central America so I can't speak to those places. Seeing an old friend sounds really appealing though, so maybe Colombia?
Live with intention. Walk to the edge. Listen hard. Practice wellness. Play with abandon. Laugh. Choose with no regret. Continue to learn. Appreciate your friends. Do what you love. Live as if this is all there is.
--Mary Anne Radmacher