I don't know what the travel time is to Colombia or Puerto Rico (although I imagine at least the latter is less), but the cost per day and travel time of going to Spain for just a week would take it off of the list if it were me. I think you should hold off on that trip until you have more time. That said, I'd love to go to Valencia.

I've never been to South or Central America so I can't speak to those places. Seeing an old friend sounds really appealing though, so maybe Colombia?