Emily, I have had good luck using Cortisone-10 on irritated bits; clears them up nicely, and I'll use it before a ride sometimes, too, to ward off developing a sore. In fact, I read a suggestion for Cortisone-10 here; looking for a solution to a persistent saddle sore is what led me to TE in the first place. And wow, was I (am I) ever grateful!!