Yes. Its best to think about dosage as an amount of synthroid per unit of body weight. So, the absolute dosage stays the same, even if the amount of each daily pill varies with body weight.
This is true for all medications, but usually dosage isn't as sensitive so it doesn't get adjusted (there is just a child dose or adult dose). Sticking to the same brand of thryoid medication is also important, not because one brand is 'better' but because even the fillers that different manufacturers use can effect absorption rates, and because our bodies are so sensitive to fluctuations if you work out your dose with one brand and then change brands the dose may be off.
But none of this is meant to scare you. Thyroid meds work great, you just need to find the right dosage, and if just synthroid, or combo therapy is right for you. You need to be patient, because it takes about 3 months to really see the effects of a change. My best advice is to work with an endocrinologist with a good reputation in your area. I started with my internist, but needed an endo to get it right (because of my need for combo therapy).





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