Sending flowers either to the coworker's home or to the funeral home would be appropriate. Where I work, it's a small group (20 people) and we keep things fairly personal, so we've sent flowers or a plant and also a card (passed around the office and signed) to the coworker's home. If a funeral or memorial will be held out of town, though, it might be more appropriate to send the flowers and card to the funeral location (delivery arrangements are usually easier - you can arrange delivery in time for the service when someone is sure to be there).

Deb