A lot of my coworkers are on depression and/or anxiety meds, when we have work meetings or pot lucks the general consensus is they are terribly unhappy. I understand clinical depression (was a mental health clinician for 15 years), but I'd say only two of them meet that criteria (out of 20), so the rest just seem miserable because they hate their jobs, home life, spouse, lack of money, their kids, the weather, etc.
Didn't you say you worked in a library, Pax?