I don't know for any real sustained climbs, but I've got to assume that even when you're climbing continuously, the grade will vary, and that means changes in your body mechanics. When I get into the flatlands, it's a whole 'nother thing because my body position just doesn't change, whether it's 10 miles or 30 or 100 (actually 45 is the longest I've been able to cope with riding on the flats... it's like a treadmill, except with dirt and grit. Yeccch.)