Yes. Sometimes it's just a matter of reinstalling the tire and making sure that the bead is well seated in the rim.
However it can also be a sign that there is a defect in the tire and that can lead to pretty catastrophic consequences if it's on the front wheel of someone who, like me, likes to go down hills really fast.
I'd take the wheel/tire/tube combination apart and inspect the tire really well, put the whole thing back together, inflate at max psi and inspect really carefully again.



It was the strangest thing!
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