Hi - I am now riding a Selle Italia Ldy saddle on my road bike. This saddle has a cut out and is women specific to fit our bodies better and to improve riding comfort. The Ldy saddle has made a world of difference in my riding comfort. It is night and day - I actually enjoy riding my bike now and can spend more than half and hour in the saddle without thinking about how uncomfortable I am. I am a true believer in women specific saddles!
I decided on the Ldy saddle after demo'ing it from my local bike shop. If you are in the market for a new saddle, and can try out a couple of different ones (e.g. Terry makes some great women specific saddles as well), it might help you make up your mind.
Hope this helps!
sjc