I've got a 105 triple on mine too (long cage Ultegra RD) and I don't think I've ever dropped a chain (touch wood).
I suspect my FSA crank played a role. I've heard a lot of chain-dropping issues happen with the lower end FSA cranks, so it probably wasn't a Shimano/105-specific issue. Now I have SRAM Rival cluster with a Force crank, so there's no 3rd party issues to contend with.