My friend's dogs are on drugs not because of their natural behaviors but because she and her husband have them in an environment that is not suitable for their energy level. So, they are acting out by destroying everything in sight and running off at every opportunity. Granted, it could be that they're just not well bred examples of the breed. But I am willing to assume that it's more about them being under exercised and alone all day. They have two small boys, two busy careers and a small house. The dogs are an afterthought most days.