I agree that Ultegra is the best bang for your buck. I do prefer Shimano over SRAM. It's mostly a personal preference, but as a mechanic, I find most SRAM stuff to be extra finicky.
When money is no object, Di2 all the way. The shifting is amazing and the battery gets around a thousand miles per charge. There's an indicator to give you an idea of how much power is left.
Congrats on the new frame!



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