I had clipless pedals (Shimano M520s, to be specific) on my hybrid (which I sold last year). I don't see lots of hybrids or mountain bikes with clipless pedals, but at the end of the day, my feeling was that it was *my* bike and the only opinion that mattered was mine, so I should put whatever I want on it. I was extremely happy having my hybrid set up that way, and I put a ton of miles on that bike.

I love using clipless pedals. During a cold snap this winter, I switched over to platforms so I could wear heavy hiking boots for my commute. Although it was really nice to wear whatever shoes I liked, when warm weather returned I couldn't wait to wrench those suckers off and get back to clipless. My understanding is that not everyone feels the same way.

Can't comment on your personal ergonomics. I find that I have less knee pain with clipless, but I have no idea whether that's because I use a different set of muscles with clipless vs. platforms, or simply because I am less tempted to mash on the pedals.