I found it left a little less of a layer. Eh, I just fill the bottle with hot water and dish soap, let it set while I shower, and then use a bottle brush to clean it. I have found Gatorade to be worse, and haven't tried any other drink. I was not the greatest with cleaning the bottles, but after my DH yelled at me for ignoring stuff growing in there, I have been religious about it.
Just don't look in my Camelbak, though. I don't put anything but water in there, and don't use it very often, but when I first started riding, I didn't know you could buy the special long skinny brush to clean it. I won't tell you the rest. I got a new one...
2015 Trek Silque SSL
Specialized Oura
2011 Guru Praemio
Specialized Oura
2017 Specialized Ariel Sport