If you currently have a 'road' rear derailleur, you'll need to get a mountain rear derailleur to use that cassette.
Shimano road derailleurs--even if they are the long cage for a triple up front--only can handle 27 teeth max, so that's why the biggest road cassettes from Shimano go to 27. SRAM goes to 28. Now, as far as your wheel hub goes, Shimano and SRAM are interchangeable (not true of Campy). And I have heard that a Shimano RD can be pushed to 28.
For more teeth, like a cassette with 32 or 34 teeth, you must use a mountain derailleur. As far as shifting under load, one thing you can do is get a 'low-normal' RD. This will make the moving to easier gears (bigger cogs) easier, but it will change your right STI (controls the rear) to a configuration opposite of a road or top normal mtn derailleur.




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