Go for it! There were loads of Americans over there this year, especially as Lance has been so successful.

I have a friend in Italy who works for a company who runs cycling holidays for Americans. She does guided rides in the Dolomites and it's getting pretty popular.

Another friend from my cycling club rode up Alp D'Huez earlier in the year and although it took her a while she did it.

PS- I heard Sheryl Crow's done the climb in 90mins. I guess she's finding new ways to Have some Fun...