I recently learned that there is more to knee pain than saddle height and (if you are clipped in) clip positioning.
My spin class instructor told me to ride knock-kneed, with my knees almost touching the top tube, to provide stability especially during sprints. I had first gotten that same knee pain on the only bike tour I've done (744 miles in 10 days). Then it came up two years later when I joined spin class last month. I am excited that I learned something in spin class that is applicable to road riding!
2009 Trek 7.2FX WSD, brooks Champion Flyer S, commuter bike