I can't help you on this directly but am wondering something. By my choice I've never had ANY hormone replacement even though I've nothing left of my reproductive system (all was removed at age 49). Balancing out hormones can be tricky - and also it isn't an intuitive process. For example, when certain parts of my thyroid hormones get too low - they actually lower my replacement rather than increasing the dose (I don't have a thyroid either). It's counter-intuitive and I'm sure it isn't the only hormone that is that way. What does your doctor say?