I've had 2 goatheads (on different occasions) with my slime tubes. I pulled out the goathead, spun the tire a bit, filled it with CO2 and was on my way. And, yes, that's on a road bike. One goathead puncture was so bad that the slime literally squirted out the hole. But that slime took care of it. That was actually last month, and I'm still on the same tube and tire. In fact, I did a century on it yesterday!



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