When I saw this thread title, I jumped right in.

I'm 47, always been active... mostly running but some triathlons in my past.
Incredibly healthy with low resting pulse, low BP, cholesterol, etc.

In the past year, I've relied on cycling for my cardio workouts. 30 years of running has taken it's toll on my knees...

Two days ago I went to the doc and BP was 142/72. I freaked. All I can think about is I'm not getting as good a cardio as when I ran all the time?

(Also, I agree with Grog re pharmaceutical industry...)