I remember that road. Couple of years ago, I camped at Crane Flats. It's definitely not a rideable road. The shoulder is very narrow and the RVs and trailers drive right over the shoulder in the S-curves. There's also a narrow tunnel that you'll have to traverse. You'd have to take the lane through the tunnel. I didn't see one cyclist on this route.
After I've given you all these hazards to consider, I'll answer your question. There are a couple slight inclines on the road down the valley floor. Nothing too steep.
Perhaps you'd like to consider limiting your cycling to the Valley Floor. It's not terribly challenging since it's flat. However, it's a gorgeous ride. I think you could get +15 miles just on the floor itself. Just watch out for all the sight seerers who are busy craning their heads towards the sky. This includes drivers too.



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