I too suffer from thyroid disease (Hasimoto's). The effects of hypothyroidism are far reaching (dry skin, numbness, feeling cold, weight gain, constipation, etc). I am to this day amazed at how taking my little pill the morning has turned my life around - gone are the days of extreme fatigue, unexplained weight gain (when I gain weight I know it is because of my eating habits now), not running around in 90F temps in long sweat pants and a sweat shirt, etc.

I too am forgetful so I found it helpful to put a pill box next to the bathroom sink along with a bottle of water. I take my pill first thing in the morning (given the bathroom is the first room I visit every morning I figured I might remember my pill if I put it there). The pill box also serves as a visual reminder and keeps me from taking multiple doses. It is important to take this medication on an empty stomach (at least 1 hour, perferably 2 hours before a meal). I've read that one should also avoid dairy products +- 2hours so as not to reduce the absorbtion of the thyroid replacement (I don't know how true this is but I do try to follow it as best I can).