Since this is not a visual medium I would recommend you go to a bike shop to check this out but setback refers to the post angle. Imagine 90 degrees from the ground straight up and down and then angle the post away from 90 degrees - that is your setback. Some seatposts are setback more than others affecting your reach etc. If you switch out for a more setback post, you may have to adjust your handlebar stem (make it shorter).
As to 1 vs 2 bolt. I use a 2 bolt - its a safety issue but I've never had a problem with a one bolt. Setback has nothing to do with the bolts.
Now I have had the saddle rails break - that's a whole other issue!



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