Very true. In a lot of remote areas of Nebraska, seeing someone way out there riding a bicycle on gravel would have some locals dropping their jaws. Other areas, though can be very bike friendly. These tend to be in pockets, here and there, depending on how popular biking is with the locals. A good way to check is to see where the bike shops are in a particular region.
As for visibility, you can't be too visible. Don't forget the bright clothes, too.