I am pretty sure my osteoporosis was influenced by the many courses of prednisone I took in the 80s, along with a few other meds. My asthma was really bad right before Advair and all of that was invented, so not as many choices. In fact, my allergist in Tempe was one of the main inventors of Advair, which I found out because his brother (a psychiatrist) lives in Acton and was tangentially in my social group for awhile.
I do have a family history of osteoporosis, so I don't think the meds are the whole cause, but it seems like some of the stomach meds I have taken are also implicated in bone degeneration.
When I went to a pulmonologist about the scarring on my lungs from Valley Fever a few years ago, he was not concerned at all about having to take a rescue inhaler for occasional wheezing. It just so happened I was recovering from bronchitis and having some residual wheezing at the start of the cycling season when I went for the consult about the "spots" on my lungs that freaked out my PCP.
2015 Trek Silque SSL
Specialized Oura
2011 Guru Praemio
Specialized Oura
2017 Specialized Ariel Sport