46T will work just fine as a large chainring. Cyclocross riders do it all the time and lots of people use them on winter bikes when we have no business using a 53 anyway.
Well, technically the issue isn't that the gears aren't tall enough. As said above, the typical 50x11 top gear of compact is actually a higher gear than the typical 53x12 of standard gearing.
What is more likely happening is that at a fast pace you have fewer high gear options because the 50T gets you into "midrange" sooner. For normal people this is a good thing. For peloton riders it can be an issue.
50x 53x
11 122 ----
12 112 12 119
13 104 13 110
14 96 14 102
15 92 15 95




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