I can tell you that I've always been happy on my Cannondale SuperSix (comparable to Amira), even during 147ish mile rides across the state of MI. It's a stiff, "aggressive" frame, but it works well for me. My previous bike was the same size Synapse (comparable to Ruby) and it felt too upright and soft to me.
All of this is a very YMMV sort of thing. The bike you will be fastest on is generally the one that fits best, assuming comparable bike weight. If you're uncomfortable anywhere it will waste a lot of energy.




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