Yes.

I'm allergic to cats. One day a few years ago, a friend came over to my house to spend the afternoon. He gave his cat some medication and playtime right before he came to my house. He wasn't covered in cat hair by any means, but he did handle the cat right before coming over. While he was at my house, he sat for a while in my recliner chair. Later that evening after he was gone, I sat in my recliner to read a book, and started breaking out in hives.