I've tried Sealskinz before, and was not impressed. They are nicely shaped and fit well, with good details. But the waterproof layer seemed to be on the inside, closest to my hand. So when I rode through proper cold rain, I ended up with heavy, soaking, ice-cold gloves, that just didn't happen to let the water all the way through. In addition the inner liner detached from the outer very easily when I took them off, unless my hands were bone dry, which doesn't happen when I ride a bike. The liner was a bear to put back.

Mind you, they may well have improved the design since then, but be sure to ask. My solution these days are neoprene paddling gloves when it pours, and get wet otherwise.