When I had a triple I only ever used the big chain ring when I was doing spinning tapes on the indoor trainer. I mostly used the middle ring, and used the small ring for steep hills.

With the compact double, I mostly use the smaller ring. When I use the larger one it tends to bother my knee (I have a patella tracking problem), though I do sometimes use it when I know I'll be on flat ground for a while. When the cassette wears out and needs to be replaced, I plan to have a chat with the LBS folks about possibly getting a smaller large chain ring so that I'll have something I can use with less pain.