I have not tried depo, but I've been taking a single-dose BCP with only 3 breaks a year for quite a few years and love it. I've been fortunate to be able to handle any BCP I've tried, as long as I take them at night, and the single-dose means there's no real cycle - steady state all the way through. No down time at all, including no PMS. Yay! Again, this may not be for everyone, but I like the idea of taking an innocuous little pill all the time better than having something injected that last for months....that may have unpleasant side effects! OH, yeah, and during those 3 breaks, I get many of the symptoms (bloating, discomfort, etc), but very lead bleed-out.

Every one is unique in these things. If I were you, I'd be hating the depo big time and would try out a pill option instead. but that's just me - your mileage may vary.

Good luck!

Namaste,
~T~