I had a screw in my heelbone after ankle surgery years ago. I had it removed 6 months after it was put in, because it made the back of my heel unbearably sensitive -- one day I accidently hit the leg of a chair with it, and I literally saw stars like when a character in a Bugs Bunny cartoon gets hit on the head.

I was also having problems with scar tissue in my ankle, and the surgeon addressed that in the second surgery.

I haven't had any problems as a result of having the screw removed. They told me the hole would just fill in.