I have had a kindle for two years and love it. I just bought the Kindle Touch yesterday. My husband wants one for Christmas and I decided to upgrade mine as well.
It does take a few minutes to adjust as a leftie. So if you hold the kindle touch in your left hand you have to reach in about an inch to touch and turn the page.if you touch the left edge it goes back a page. It only took me a few pages to adjust to moving my left thumb in when I held the kindle in my left hand. I probably hold it in my right hand more often. When I read a regular book I turn pages with my right hand so didn't think this was a big issue.