I tried about 6 different saddles and bought about 3 before I found the right one (a Specialized Ruby 143 on my Specialized Dolce) but... then I started racing and switched to a different bike with more aggressive geometry and the Ruby completely cut off blood supply to my legs

I am EVENTUALLY happy and super comfortable with a saddle by John Cobb. They look fairly bulky but I promise they are amazing. There is also a 180 day money back thing so you don't end up with 3 extra saddles that make your butt hurt sitting in the closet!

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2010 Cannondale Supersix HiMod 1/Cobb V-Flow
2005 Specialized FSR XC/ Specialized BG Jett