Thanks, Anne. No, I'm not a runner, just a cyclist and I do yoga too. I injured my calf (same leg) back in May. That injury was caused by doing calf raises, which made the muscle pretty sore. Then, instead of taking an additional rest day, I did a ride that ended up being hard and fast. My calf ached. It was basically in the middle of the big calf muscle and then extended up the outer leg to just below the knee (sorry, that's the best way I know to describe it).

I eased off riding and was feeling better. Then I ended up on another fast group ride and came home with the calf and the popliteus pain. The calf now feels much better and just kind of tight during long rides.

The popliteus hurts the most from the 5-7'o clock postion on the pedal stroke. It hurts less with a high cadence and when I climb (as I tend to shift back in the saddle). The pain is more toward the outside of my leg, just offcenter of the back of the knee.

Hope this helps and thank you for your input! I'll start with the saddle and also take a look at my cleats.