Which Road bike should I buy?

[Owlie]

Do you need a women-specific frame? What's your inseam?

There's actually very little difference between Giant's unisex and women's frames. I think the biggest thing is that they shave off half a centimeter of top tube (beyond short-reach shifters and perhaps narrower bars, which are easy enough to swap out, though it will add to the cost.) So if Giant's geometry works for you, go for it--and feel free to pick on the basis of color if that's the case. (And I agree with you on the colors. I want red and black, but no one puts it on WSD bikes. )

You could, for comparison purposes, look at Specialized, but they tend to be even more expensive than Cannondale.