I will be Captain Obvious here and ask if you have changed the detergent you are using for laundry. If the latex is old or silicone is older in your shorts, it might just be breaking down a bit and causing a rash. Are you shaving higher on your legs since starting to wear shorts and the growing in hairs are irritating the area?
I know, dumb ideas, but sometimes simple is the most obvious answer. You could try putting some vaseline on the area before you ride and see if it helps.
“Experience is simply the name we give our mistakes.”.
~Oscar Wilde
Type One Diabetes
currently using Medtronic MiniMed
Revel 723 with CGMS