I can SO relate to this statement. I am on my 3rd bike in as many years, and I am, once again, contemplating a new one. I've had 3 professional fittings (including a very expensive RETUL fit) and still can't seem to get comfortable enough on longer (50+) rides. It's been very frustrating, to say the least. I'm starting to wonder if the 51cm bike I am currently on, is a bit too small for me. I'm tired of sinking money into pro fits, saddles, and stems in order to make this bike work for me. I too, am looking into a Madone 5.2...as well as a Cervelo RS, an Orbea Onix/Dama TLT, a Felt Z series, and a Specialized Ruby. I've been riding a road bike for 3 years, yet I feel as though I'm starting back at square one again.
Linda