Bicycle Wheel Warehouse has a 105/Open Pro wheelset for $299.99 and a 105/Open Sport wheelset for $229.99. Either would serve you well.

On my road bikes, I have 32-hole Velocity Deep V rims with Ultegra hubs that I've been really pleased with. They're handbuilt, and outside of your budget, but it's another combo that heavier riders really can't go wrong with.