Yep, I use clipless pedals for commuting on mostly urban streets. I can't imagine riding without them, to be honest.

It takes some practice, especially at the beginning. I suggest a double-sided mountain-style pedal. They're easier to to clip in and out of IMO, and finding a double-sided pedal is easier in traffic. The other option is "campus-style" pedals, where one side is SPD clipless and the other side is flat.