You might be able to negotiate time off to equal your current position. That's something that is very important to me; I would not go from 4 weeks off to 2 weeks off. No way!

Flexible work schedule is also extremely important to me, but it might be something that you can give up for the other plusses--that is up to you.

Seriously consider the travel part. How long would they put you with clients? How far away?

Since this is a bicycling forum (at least officially), you might want to consider the bicycle-commute friendliness also. That would be huge with me, but it may or may not be an issue for you.

You might want to consider making a simple list of pros and cons. Sounds like a silly exercise, but I've found it very useful for all sorts of situations.

See what the offer letter says and treat it as a starting point.

Best wishes to you!