I have been riding about 2 years now (with about a 25 year break). I've gone thru 3 bikes since starting. My first bike was a Specialized Globe hybrid. It definitely was comfortable and easy to ride, but heavy and slow. I felt like W would never fall off of it. The transition to my next bike - Specialized Vita - was easy and I wished I had bought that one first. Then I got my road bike - Specialized Ruby. I had no problem transitioning to that bike. It was perfect and not at all twitchy.
I think that some road bikes have more aggressive geometry than the Ruby. Those bikes might feel more intimidating.
2007 Ruby Comp/Specialized Dolce
2004 Bike Friday Crusoe/Specialized Dolce