I was wondering how long you've had your current setup and were you properly fit? As I'm picturing your riding position, it sounds like you're putting more pressure on your hands and wrists and that is aggrivating your wrist condition. How high is your saddle compared to the height of the top of your handle bars? I'm told that it's supposed to be between 0-2 inches. I find that if the bike is too small, I have to raise the saddle higher which then tilts my body forward and places more pressure on my wrists and hands. I ride with bull horn bars and I had to experiment with getting the most comfortable position. Because the bull horns are flat and somewhat curvy, I was placing too much weight on my hands. I raised my bar height and tilted it up a little and that seemed to fix the problem. Although, you may want to have a doctor examine your wrists to get a diagnosis and rule out any carpal tunnel or arthritis problems. It may cost you some money but at least you'd know if it was a medical condition or just a simple bike accessory/fit issue.