OK, well I actually had to stop drinking wine for about 15 years . It started when I was in a particularly sensitive period, with asthma, etc. That definitely was sulfites. I also realized they were the cause of an asthma attack/allergic reaction every time I had the soup at my school lunch; there must have been sulfites in the mix. So the "sleepy" feeling in wine could be the sulfites. Now, you can buy sulfite free wine. However, I got sick of always drinking beer, so one year at Passover, I decided to test out my body by partaking in the wine drinking part of the ritual meal. I was fine. Since that was in 1996, I guess my allergy has gone away.