I am 5'3 and 1/2 and I am on a 29er. Salsa Mamacita. It depends on your geometry and the bike's. I do not have any standover room, but that does not bother me. What does bother me is that it is tough to bail off of when I need to. It is a long way to the ground for short people.

You may have to have one costum built, which would be pricey.

One thing I will tell you, is that for small women, you will need very light wheels and I would suggest going tubless. I started with stock wheels and had a hard time getting the bike to repsond because of the rotational mass of a heavy wheel.

We just upgraded to Stan's Crest tubeless and what a huge difference. It is like a new bike.
Good luck. I love mine.