Glad to report back that we had no trouble at all. The hotel was right next to the San Diego Convention Center where a major convention was being held. Our room was on the 23rd floor (of 25) so we didn't use the stairs
We entered and exited thru the rear/side doors and had no problems with the elevators.
The ride itself was GREAT and we finished all 100km of it! We'd definitely do this one again and it was really nice making a weekend out of it 
Thanks for all the helpful advice!
2011 Pinarello FP2 Ultegra (road)
2010 Jamis Ventura Comp w/Selle SMP (road bike)
2007 Fuji Absolute (hybrid)