I sprained my ankle saturday before last. I couldn't walk on it for two days, just on crutches. the third day, I was walking with one crutch and started hobbling after that. Today, I tried running on it and I was fine. It still hurts if I turn it in too much, but I don't have any discomfort when I ran. It is still a bit swollen and discolored, but all and all, better than I expected. I iced it after I ran and I am icing it again now. I am going to try to get in a short ride tomorrow. I expect that since running didnt bother it, cycling won't either.