Here is one from the minority. I have a multi-sport bike that has a 76 degree seat angle with all-in-one aerobars. This happens to be my everyday bike. I did add an adjustable stem to bring up the height of the handlebars to increase my comfort. I do have some back,neck and joint issues, and for me this bike has been incredibly comfortable to ride. I like to go for long rides and at times I like to go fast. I have climbed some steep hills too. Only caveat, I almost wiped out taking some corners too fast. My old road race bike had become too painful to ride for any length of time. I am not promoting buying a such a bike in general, just wanted to add my experience.

I brought up this question here before, and it came shortly after I started researching new bikes. I noticed the difference in seat angles of the same model bike, but in the different sizes. For example, the Trek Madone 5.2-- has a seat angle of 75.5 and head angle of 70.2 in the XS (47cm) size. Whereas the L (62cm) size has a seat angle of 72.5 and head angle of 73.9. Makes the XS seem almost like multi-sport in geometry. I know I have to take the bottom bracket into consideration along with all the other parts, but I am just throwing it out there for thought.