Okay, I know you said you weren't really interested in panniers; but I've been down this road for the last two years and have bought far too many shoulder bag types.
The problem is finding one big enough that isn't to heavy to really weigh you down. That in itself is almost impossible.
I have finally found the answer to my dilemma which gets the weight off my back which really gets to you after a few miles. I've been transporting very expensive cameras, extra lenses, laptops, iPods, you name it and have never had any harm come to them in a carefully loaded pannier....a VERY lightweight set of panniers.
Here's my setup which would be overkill for most but since I no longer have a car, everything goes with me every day.
It's a combination of a set of panniers and a messenger bag both made by Axiom and purchased through Amazon. The messenger bag was about $30 and the panniers were about $40. Being very lightweight and water resistant, they aren't padded at all. Just use a laptop sleeve, and pack your clothing around it.
I could wear the messenger bag on my back but I prefer to strap it on top of the panniers. I HATE having anything on my back.
Just a suggestion.
Incidentally I went the Arkel route first and spent about $200 for a quick release system that never really worked well and disintegrated in a month. They aren't padded either so I don't see any reason to spend that much for a quick release system that doesn't work. The fabric also wore out at the stress points very quickly as well. On both of the panniers.





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