I'm really sorry - I know it's very hard to see someone you love suffer.

I've been reading about some promising research recently on HIV/aids but I'm not sure whether it's reached clinical trial stage - but it might be worth researching to see if it's an option for your brother. Basically they did "cure" HIV in one person a couple years back by happening to be able to give them a bone marrow transplant from a CCR5- donor, so that the new immune system was HIV resistant. Since the odds of a MHC compatible bone marrow match that happens to be CCR5- are fairly low, there's various efforts to be able to genetically engineer bone marrow stem cells to suppress CCR5 expression.

clinicaltrials.gov should have a list of any HIV trials that are being done.

This might help:
http://investor.sangamo.com/released...leaseID=363201